Regulation of Hemoglobin A1c Levels in Type II Diabetes Patients Using Probiotics

Croft, Anthony

Diabetes mellitus is a group of chronic diseases that affect the body’s ability to utilize the energy in food resulting in high blood glucose levels. Poorly controlled diabetes mellitus can lead to complications such as: cardiovascular disease, nephropathy, neuropathy and retinopathy of the eye, which can result in blindness. Prior research shows that the introduction of probiotics into the diets of people with Type 2 diabetes mellitus (T2DM) decreases hemoglobin A1c (HbA1c) levels, glucose fasting sugar levels, and improves insulin resistance. The goal of this proposed pilot study is to identify the mechanisms of action in probiotics that positively affect HbA1c levels. Conclusions from the literature review will inform the study intervention regarding the impact of probiotics on glucose outcome measures in persons with T2DM.